Burzynski going ka-boom

First, a nice bit of news: Marc Stephens, the lunatic who stirred up the recent blogospheric buzz with his clumsy thuggery, no longer has a “professional relationship” with the Burzynski clinic, that warehouse of quackery. One thing about charlatans is that they have a fine-tuned sense of who might be hurting their bottom line.

But the damage has already been done. The Burzynski clinic is getting scrutinized.

Josephine Jones is tracking all the commentary.

And this is rich: Jen McCreight digs into the Burzynski publications list. Would you believe it’s a collection of marginal, low-impact journals and unreviewed conference presentations? Yeah, I knew you would.

(Also on FtB)

Burzynski Clinic: the domain of scoundrels and quacks

Billie Bainbridge is four years old, and she has an inoperable brain tumor, and her prognosis is not good. Her family is desperate, and has been frantically trying to raise money from the community to cover the costs of a treatment they’ve been told might cure her. They need £200,000. They are asking the public to contribute.

Unfortunately, the treatment they want to give her is antineoplaston therapy: it’s pure bunk. The clinic that is trying to suck large sums of money away from the family of a dying child is the Burzynski clinic. So in addition to being a quack, Burzynski is now a vampire, exploiting sick children for profit.

Andy Lewis wrote an article about the false hope of the Burzynski clinic. It’s damning — the Burzynski clinic has been exploiting the sick for years with an exorbitantly priced ‘therapy’ that has never passed Phase III trials.

A scientific organization would respond to such an argument, you would think, with a deluge of data and explanations of the scientific basis of their treatment. Not the Burzynski clinic! Instead, they have some angry hack at their establishment who fired off a whole series of threatening letters to Lewis, claiming legal authority with no evidence that the angry clown, Marc Stephens, has any legal credentials at all. There’s certainly no science behind his rants, and there doesn’t seem to be any legal standing, either.

So Stephens threatens Lewis’s family.

Be smart and considerate for your family and new child, and shut the article down..Immediately.

You can guess how the Internet responds to such thuggish, bullying behavior: by blowing up and pointing out even more loudly the deficiencies of the Burzynski clinic.

So Stephens has started sending these threatening letters to other people, including Rhys Morgan. “GOVERN YOURSELF ACCORDINGLY,” he blusters as he promises libel suits.

I think you all know what to do now. Spread the news of the Burzynski clinic’s quackery far and wide; trumpet it loudly everywhere. The media has been fairly passive about this abuse of children and dying adults for some time now, so let’s make it clear to the world exactly how contemptible these phonies are.

GOVERN YOURSELF ACCORDINGLY.

(Also on FtB)

The Quran is bunk, too

I know you kids like the youtube and hate that tl;dr text stuff, so if you couldn’t find the patience to read my post on Islamic embryology, you can now watch the screen instead. The Rationalizer goes through the ‘science’ in the Quran and shows that it’s largely plagiarized from Galen, and that it also steals Galen’s mistakes, so it’s a beautiful example of a plagiarized error of the type biologists use to demonstrate a lineage.

All the straining Muslim apologists use to fit the science to the few lines of poetry in the Quran (I’m looking at you, Hamzas Tzortzis) are futile and really only demonstrate that the founders of Islam borrowed their message, not from a divine source, but from Greco-Roman medicine.

But perhaps Allah is just another name for Galen.

(Also on FtB)

Acupuncture is bunk

Here’s a terrific webcomic exposing the silliness of acupuncture. People are always citing these awful studies at me that they claim support the efficacy of acupuncture, and like the comic says what I see when I read them is that the advocates have gone “anomaly hunting after any statistically relevant result, usually by cherry-picking data or creative interpretation. You’ll never find a conclusive effect with acupuncture studies”.

I’d really like to hook the traditional Chinese medicine freaks with the cannabinoid bozos who’ve lately been doing the same thing: citing weak results to prop up extravagant claims of near miraculous efficacy. A kookfight to the death!

(Also on FtB).

A little dose of hemp will cure everything

Do these claims make you at all suspicious? A few people on Twitter told me I should look into this panacea.

Cures heart disease!

Eases anxiety and depression!

Removes unsightly moles!

Arthritis! Snoring! Diarrhea! Acne! Diabetes! Removes warts! Mighraines! Lose weight! Alcoholism! Glaucoma!

IT CURES CANCER! All forms of cancer!

And all without any detrimental effects whatsoever!

Add to the extravagant medical claims, the additional accusation that you can’t get this treatment because of a conspiracy by BigPharma and greedy, grasping doctors who want people to suffer so they can charge them lots of money to fix them with agonising tortures that don’t work.

Are you suspicious yet?

These are all claims Rick Simpson and a small group of Canadians make for hemp oil in this video.

You may not want to watch it — I’ve already given you the gist of it, and it’s repetitious and very poorly edited (hint: just because your home movie editing software has a lot of exotic transitions, doesn’t mean you have to use them all). It looks like an infomercial, with a parade of Nova Scotians offering wild anecdotal claims of all the stuff a daily dose of hemp oil cures. These testimonials are presented as the evidence that hemp oil is medically efficacious; they aren’t. Quite the opposite, actually — it all says to me that the promoters found some marginally sick people and fed their desire for wish-fulfillment, and got a slew of meaningless accolades and bizarre conspiracy theories that tell me that what’s going on here is psychology, not medicine.

It’s not just religion that kills people. I watched Rick Simpson claim that he had skin cancer, and that rubbing his marijuana extract healed the lesions overnight, and I thought… people may well die from watching and believing this claim. Some forms of skin cancer (melanoma) are extremely aggressive and dangerous — do not delay, do not play games with weird magic topical creams, get a real doctor to check it out.

The information on the video also gives off a bad vibe.

The following presentation of RUN FROM THE CURE: The Rick Simpson Story was made possible by Rick Simpson and video producer Christian Laurette… made for free to teach YOU how to heal yourself of disease and illness using cannabinoids.

Comments will be moderated to protect those who need this information. We are not asking anyone if it works, we are telling you it works; it is not a debate. Too many uneducated people coming to this channel to speak their mind on a life-saving plant they know nothing about and giving bad advice and in many cases making horrible remarks about the people who brought the information out to you.

No argument! If you disagree with him, you’re uneducated…despite the fact that the pro side consists of rural citizens who seem to know nothing about how to interpret evidence, while his opponents are doctors and scientists.

The video also lies, lies, lies. I’ve often heard quacks say this: “FACT: Chemotherapy kills more people than it saves.” It’s not true. People who are on chemotherapy are more likely to die than people who are not on it, because the only reason those people are on chemotherapy in the first place is that they are really, really sick. It makes nonsensical claims: “THC attacks mutated cells while rejuvenating healthy ones”. How do they know? These aren’t scientists making the claims, these are ordinary townspeople — Simpson makes his formula by doing a crude extraction with naptha or isopropyl alcohol in a bucket he stirs with a stick, and boils it down to an oily residue in a rice cooker (there will be an explosion and fire at his house someday, I predict). He has no tools to examine specific cellular responses, so the source of these claims of a mechanism are being taken directly out of his ass.

At least Simpson is giving his cure-all away for free — all he’s doing is feeding his over-inflated ego at the potential cost of a few lives. He’s not quite like the odious Burzynski Clinic, which bilks people for hundreds of thousands of dollars for an extravagantly promoted therapy that has no good evidence for its efficacy. And at least he has not resorted to threats.

But he’s still a dangerous quack and a crank.

One other thing: I’m all in favor of legalizing marijuana and ending the phony drug war that turns harmless folk into criminals, jacks up the cost, and entices violent thugs into what ought to be simple farming. If you look up Rick Simpson, though, you find all these groups advocating legalization also buying into Simpson’s hazardous and dishonest game. That only discredits the legalization movement.

(Also on FtB)

Islamic embryology: overblown balderdash

I have read the entirety of Hamza Andreas Tzortzis’ paper, Embryology in the Qur’an: A scientific-linguistic analysis of chapter 23: With responses to historical, scientific & popular contentions, all 58 pages of it (although, admittedly, it does use very large print). It is quite possibly the most overwrought, absurdly contrived, pretentious expansion of feeble post hoc rationalizations I’ve ever read. As an exercise in agonizing data fitting, it’s a masterpiece.

Here, let me give you the short version…and I do mean short. This is a paper that focuses with obsessive detail on all of two verses from the Quran. You heard me right: the entirety of the embryology in that book, the subject of this lengthy paper, is two goddamned sentences, once translated into English.

We created man from an essence of clay, then We placed him as a drop of fluid in a safe place. Then We made that drop of fluid into a clinging form, and then We made that form into a lump of flesh, and We made that lump into bones, and We clothed those bones with flesh, and later We made him into other forms. Glory be to God the best of creators.

Seriously, that’s it. You have just mastered all of developmental biology, as taught by Mohammed.

Tzortzis bloats this scrap into a long, tedious potboiler by doing a phrase by phrase analysis, and by comparing it to the work of Aristotle and Galen, who got lots of things wrong. How, he wonders many times, could Mohammed have written down only the correct parts of the Greek and Roman embryological tradition, and avoided their errors, if he weren’t divinely inspired? My answer is easy: because Mohammed only made a vague and fleeting reference to the science of the time, boiling down Aristotle’s key concept of an epigenetic transformation into a few non-specific lines of poetry. Aristotle and Galen got a lot wrong because they tried to be specific and wrote whole books on the subject; you can read the entirety of Aristotle’s On the Generation of Animals. Galen was prolific and left us about 20,000 pages on physiology and medicine.

So, yes, you can find lots of examples in their work where they got the biology completely wrong, and it’s harder to do that in the Quran…because the Quran contains negligible embryological content, and what there is is so sketchy and hazy that it allows his defenders to make spectacular leaps of interpretation. Mohammed avoided the trap of being caught in an overt error here by blathering generalized bullshit, and saying next to nothing. This is neither an accomplishment nor a miracle.

I’ll go through his argument piece by piece, but at nowhere near the length. It’s hard to believe anyone is using this feeble fragment to claim proof of divinity, but then, Christians do exactly the same thing.

  1. “essence of clay”. Tzortzis happily announces that clay contains “Oxygen, Carbon, Hydrogen, Nitrogen, Calcium, Phosphorus, Potassium, Sulfur, Chlorine, Sodium, Magnesium and Silicon; all of which are required for human functioning and development”. These are irrelevant factlets. Clay is a fine-grained hydrous aluminum phyllosilicate; carbon, which is the element to consider in organic chemistry, is present as a contaminant, but the primary elements are aluminum and silicon. It’s nothing like the composition of the human body. This part of Tzortzis case is simply a lie.

  2. “drop of fluid”. Tzortzis tells us that the Arabic word here is “nutfah”, which has a number of meanings, but he likes the interpretation that it implies mingled fluids. Then he babbles on about oocytes and spermatazoa and secretions of the oviduct, none of which are mentioned in the Quran and are completely irrelevant. Bottom line: Arabs noticed long ago that sex involves a mingling of fluids. Brilliant. I think most of us could figure that out without divine inspiration.

    He spends a fair amount of time pointing out that both Aristotle and Galen had a male-centric view of procreation, where the man’s contribution was the dynamic agent and the woman was a passive vessel. They were wrong. In order to rescue the Quran, though, Tzortzis has to bring in Ibn Qayyim, a 13th century Islamic scholar, who pointed out that women have to provide a significant contribution to inheritance, since their traits are also present in the children. This, again, is an obvious and observable property, and the Greeks also argued over the relative contributions of male and female. There is nothing in the Quran that is beyond casual observation or non-existent in the scholarly works of the time.

  3. “in a safe place”. Tzortzis quotes modern embryologists and throws around the terms endometrium, syntrophoblast, implantation, uterine mucosa, proteolytic enzymes, etc., etc., etc. I ask you, is any of that in the quoted verse from the Quran? No. Total bullshit from the apologists. That the embryo grows in a “safe place” — the woman’s belly — is another obvious property.

  4. “a clinging form”. It seems that the word used here means just about anything.

    The Qur’an describes the next stage of the developing human embryo with the word `alaqah. This word carries various meanings including: to hang, to be suspended, to be dangled, to stick, to cling, to cleave and to adhere. It can also mean to catch, to get caught, to be affixed or subjoined. Other connotations of the word `alaqah include a leech-like substance, having the resemblance of a worm; or being of a ‘creeping’ disposition inclined to the sucking of blood. Finally, its meaning includes clay that clings to the hand and thick, clotted blood – because of its clinging together.

    I could call the embryo a sticky blob, too, and stretch and twist the words to match it in the vaguest possible way to a technical description, too…but it doesn’t make it a technical description, and it doesn’t make it informative.

    This section concludes by claiming that the “leech” interpretation of ‘alaqah is accurate, because later in development it looks, he claims, like a leech. Only to a blind man. And further, he applies this term “like a leech” to every stage in the first month of development; the accuracy of the comparison seems irrelevant.

  5. “a lump of flesh”. More of the same. Take the Arabic word (“mudghah”), throw out a bunch of definitions for the word, then force-fit them all into the actual science.

    The next stage of human development defined in the Qur’an is mudghah. This term means to chew, mastication, chewing, to be chewed, and a small piece of meat. It also describes the embryo after it passes to another stage and becomes flesh. Other meanings include something that teeth have chewed and left visible marks on; and marks that change in the process of chewing due to the repetitive act.

    No. I refuse. I’m sorry, but this is patently ridiculous. You do not get to quote the Quran talking about a chawed on scrap o’ meat, and then go on with four pages of windy exegesis claiming that corresponds to the 4th week of human development, the pharyngula stage, as if it is an insightful and detailed and specific description of an embryo. It is not. It is the incomprehending grunt of an ignorant philistine.

  6. “into bones”. Yeah. There is a mingling of fluids in sex, and at birth you have a baby with bones. Somewhere in between, bones must have formed. You do not get credit for noting the obvious without any specifics. Furthermore, turning the phrase “into bones” (‘idhaam) into this:

    There are clear parallels between the qur’anic `idhaam stage and the view modern embryology takes i.e. the development of the axial, limb and appendicular skeleton.

    is pure hyperbole and bunkum. But then, that’s all we get from Tzortzis.

  7. “clothed the bones with flesh”. Tzortzis now talks about myoblasts aggretating and migrating distally, formation of dorsal and ventral muscle masses, innervation of the tissue, and specification of muscle groups. Good god, just stop. The Quran says nothing about any of this. And then to complain that This level of detail is not, however, included in Aristotle’s description, is absurd and ironic. It’s not in Mohammed’s description, either.

    It must be noted that the migration of the myoblasts surrounding the bones cannot be seen with the naked eye. This fact creates an impression of the Divine nature of the Qur’an and reiterates its role as a signpost to the transcendent.

    Crap. The Quran doesn’t describe myoblast migration. There isn’t even a hint that Mohammed saw something you need a microscope to see.

  8. “made him into other forms”. Then Allah did all the other stuff that he needed to do to turn a chunk of chewed meat made of bone and flesh into a person. Presto, alakazam, abracadabra. Oooh, I am dazzled with the scrupulous particularity of that scientific description.

There’s absolutely nothing novel or unexplainable in the Quran’s account of development. It is a vague and poetic pair of verses about progressive development, expressed in the most general terms, so nebulous that there is very little opportunity for disproof, and they can be made to fit just about any reasonable observation. They can be entirely derived from Aristotle’s well-known statement about epigenesis, “Why not admit straight away that the semen…is such that out of it blood and flesh can be formed, instead of maintaining that semen is both blood and flesh?”, which is also a very broad statement about the gradual emergence of differentiated tissues from an amorphous fluid.

Only a blinkered fanatic could turn that mush into an overwrought, overextended, overblown, strained comparison with legitimate modern science. Tzortzis’s paper is risible crackpottery.

(Also on FtB)

The incredible self-destructing psychologist

Holy crap. A Dutch social scientist’s career has just crashed flamingly. He apparently had a tremendous reputation.

“Somebody used the word ‘wunderkind’,” says Miles Hewstone, a social psychologist at the University of Oxford, UK. “He was one of the bright thrusting young stars of Dutch social psychology — highly published, highly cited, prize-winning, worked with lots of people, and very well thought of in the field.”

But maybe someone should have been made a bit suspicious by this behavior:

Many of Stapel’s students graduated without having ever run an experiment, the report says. Stapel told them that their time was better spent analyzing data and writing. The commission writes that Stapel was “lord of the data” in his collaborations. It says colleagues or students who asked to see raw data were given excuses or even threatened and insulted.

Graduate students who were not doing experiments, a PI who was, graduate students doing all the analysis and writing, a PI who wasn’t? This was an obvious inversion of the natural order. Human sacrifice, dogs and cats living together… mass hysteria! Such peculiar behavior should have alerted someone early on — data are primary.

And now, the denouement:

Diederik Stapel was suspended from his position at Tilburg University in the Netherlands in September after three junior researchers reported that they suspected scientific misconduct in his work. Soon after being confronted with the accusations, Stapel reportedly told university officials that some of his papers contained falsified data. The university launched an investigation, as did the University of Groningen and the University of Amsterdam, where Stapel had worked previously. The Tilburg commission today released an interim report (in Dutch), which includes preliminary results from all three investigations. The investigators found “several dozens of publications” in which fictitious data has been used. Fourteen of the 21 Ph.D. theses Stapel supervised are also tainted, the committee concluded.

Stapel has made a comment. I don’t think he understands what he has done at all.

Stapel initially cooperated with the investi­gation by identifying fraudulent publications, but stopped because he said he was not physically or emotionally able to continue, says Levelt. In a statement, translated from Dutch, that is appended to the report, Stapel says: “I have made mistakes, but I was and am honestly concerned with the field of social psychology. I therefore regret the pain that I have caused others.” Nature was unable to contact Stapel for comment.

No, he was not honestly concerned with the field of social psychology. If he actually cared about what the evidence told him about the world, he wouldn’t have made it up. He was honestly concerned with the selfish goal of making a name for himself, nothing else.

He’ll never be trusted in any field of science ever again. He’s going to have to look for a new career…maybe theology, where making up data is a way of life.

(Also on FtB)

Traces of a Triassic Kraken?

At first I thought this discovery was really cool, because I love the idea of ancient giant cephalopods creating art and us finding the works now. But then, reality sinks in: that’s a genuinely, flamboyantly extravagant claim, and the evidence better be really, really solid. And it’s not. It’s actually rather pathetic.

It consists of the discovery of ichthyosaur vertebrae lying in a flattened array. They look like this.

i-08915103555b433da4ec5af02502d78a-shonisaur.jpeg
Photo shows shonisaur vertebral disks arranged in curious linear patters with almost geometric regularity. The arranged vertebrae resemble the pattern of sucker discs on a cephalopod tentacle, with each vertebra strongly resembling a coleoid sucker.

Wait, what? That’s it?

This work was presented at a meeting of the GSA under the title “Triassic kraken: the Berlin ichthyosaur death assemblage interpreted as a giant cephalopod midden “, with this argument:

“It became very clear that something very odd was going on there,” said McMenamin. “It was a very odd configuration of bones.”

First of all, the different degrees of etching on the bones suggested that the shonisaurs were not all killed and buried at the same time. It also looked like the bones had been purposefully rearranged. That it got him thinking about a particular modern predator that is known for just this sort of intelligent manipulation of bones.

“Modern octopus will do this,” McMenamin said. What if there was an ancient, very large sort of octopus, like the kraken of mythology. “I think that these things were captured by the kraken and taken to the midden and the cephalopod would take them apart.”

In the fossil bed, some of the shonisaur vertebral disks are arranged in curious linear patterns with almost geometric regularity, McMenamin explained.The proposed Triassic kraken, which could have been the most intelligent invertebrate ever, arranged the vertebral discs in double line patterns, with individual pieces nesting in a fitted fashion as if they were part of a puzzle.

Even more creepy: The arranged vertebrae resemble the pattern of sucker discs on a cephalopod tentacle, with each vertebra strongly resembling a coleoid sucker. In other words, the vertebral disc “pavement” seen at the state park may represent the earliest known self portrait.

Let me explain something here. This “Triassic kraken” has not been found; no fossils, no remains at all, no evidence of its existence. It is postulated to have been large enough to hunt and kill ichthyosaurs, which is remarkable—comparison to modern giant squid is invalid, since they are prey, not predator. This fossil bed is being over-interpreted as a trace fossil, with the bones arranged by intent, by an intelligent cephalopod, which they have not seen. Furthermore, a line of discs is being seen as a picture of a cephalopod tentacle, classic pareidolia. This is trivial: dump a pile of Necco wafers on a table, and I’ll see a picture of squid suckers. This is a whole series of tenuous and unlikely speculations stacked together to make an ultimately ridiculous hypothesis.

After I read the abstract and realization settled in that this was nonsense, something else was nagging me. That name, McMenamin — I’d heard it somewhere before. A little search, and there it was: I’ve encountered him tangentially before. He’s the geologist who so effulgently endorsed the imaginative pattern-spotting of Stuart Pivar. He also claims “that mariners of ancient Carthage made it to America long before Eriksson and Columbus, some time around 350 BC.”

I think I would concur with the idea that Mark McMenamin is exceptionally imaginative.

(Also on FtB)