Taking stock of the pandemic

On March 11, 2020, the World Health Organization declared Covid-19 to be a global pandemic. In the two years since then, we have passed one grim milestone after another. As of yesterday, there have been 483 million cases worldwide or 6.1% of the total population of 7.9 billion. There have been a total of 6.2 million deaths.

When one looks at the per capita death rates, apart from Peru (which has the highest rate), Brazil, and Chile, the rest of the top 20 countries for cases are in Europe or the US. In fact, the highest ranking country outside Europe and the Americas is at #35 with Tunisia. A similar pattern holds for infection rates.
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Pandemic lessons from Hong Kong

The covid-19 pandemic is going to be a rich source of data for how to deal with any future pandemics. The prevalence and degree of severity of the disease has varied widely across the globe, as have the ways in which various countries responded to it, and this has given rise to so-called ‘natural experiments’, those in which one can isolate and study the effects of individual factors without having to actually do experiments.

One of the firmest lessons is the importance of vaccinations for everyone but especially the need to vaccinate those segments of the population that are most likely to suffer adverse effects and death. In the case of covid-19, it was the elderly and the immunocompromised who were most at risk.

But there is also the question of how far to go with trying to isolate regions in order to keep the virus out of the country. The countries that practiced severe lockdowns and strict border controls (such as China, New Zealand, and Hong Kong) were initially able to keep the numbers extremely low while many other countries were suffering badly, but now the situation seems to be reversed in that the previously affected countries are seeing a decline while those initially low case number countries are seeing a spike.
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Second Republican governor vetoes ban on transgender sports

The bans on transgender athletes being proposed by Republican state legislatures are so cruel and unnecessary that even some Republican governors are taking a stand against them. Utah governor Spencer Cox has just joined fellow Republican governor Eric Holcomb of Indiana in vetoing such legislation. In doing so, he offered some heart-warming words. (All boldfacing is mine.)
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Covid-19 fatigue

I am one of the fortunate ones in that I was able to get vaccinated and boosted and since I am retired, during the worst of the pandemic I could spend most of my time at home and thus could easily practice social distancing. I also wore masks whenever I was in any indoor facility with other people. But while it was not onerous, I too have started to feel weary of taking these precautions and was hopeful that the rapid decline in cases in the recent past signaled the transition from a pandemic phase to an endemic phase that would enable us to let down our guard and just take the kinds of precautions we are used to with other familiar airborne contagions like the flu and cold, where we stay at home when we have symptoms and avoid contact with people who are exhibiting symptoms.

But now we hear reports of a delta-omicron hybrid and a BA.2 version of the omicron variant causing a slight uptick in cases in Europe and the UK, which in the past have been leading indicators of what would happen in the US after about two or three weeks. 45% of the US population has been infected with omicron and thus have some immunity to that BA.2 version of it but that still leaves a large number at risk.
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A set of podcasts worth browsing

A friend alerted me to the existence of this series of fascinating BBC podcasts called In Our Time. Each 40-50 minute episode consists of the host Melvin Bragg exploring one topic in depth with three academics from various British universities and research institutions. Originating in 1998, it produces a new episode each week and by now its archives have close to 1,000 podcasts. Each episode also has a comprehensive reading list for those who want to know more. The topics range all over the place, covering science, history, literature, art, religion, and so on so that anyone will find something that appeals to them or are curious about. Since the panelists are experts in the area being discussed, one gets reliable information based on in-depth research. The program is ideal for a generalist like me.
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Absolute and relative risk

Probability can be deceptive. The concept sounds easy to understand and we glibly use the ideas in everyday life but there are many subtleties involved. Given how important probabilistic ideas are in life, some have suggested that it be introduced into school mathematics curricula much earlier than it currently is and discussed in more depth.

One subtlety can be highlighted by this example. Suppose that you read about a new study that finds that by taking some measures, you can reduce the risk of stroke by 50%. Should you adopt those measures?

To make a decision you need to weigh the benefit against the costs, which in this case may be that the measures involve taking medications that have rather serious side effects, or that the regimen involved is arduous, or that it is very expensive. But even taking those into account is not enough to decide because you need to know another key piece of information and that is the absolute risk numbers.

The relative risk is what is usually reported and quoted in the media. It is obtained by comparing the results of the test group with the control group. So if the test group has five positive cases and the control group has ten, then the relative risk reduction is 50%. But this ignores the importance of sample size that determines the absolute risk. If the sample size had been 10,000, the absolute risk would have dropped from 0.1% to 0.05%.

Paula Byrne, one of the authors of a recent study on the benefits of taking statins to lower cholesterol, says that focusing only on relative risk does not give enough information to make an informed decision.
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One time all year round? I did not see that coming

As long time readers know, I grumble about that biannual ritual in the US of changing the clocks forward by one hour in the spring (when it becomes Daylight Savings Time) and then one hour back in the fall (when it reverts to Standard Time). We just made the change this past Sunday and I went around changing the eight clocks that are not connected to the internet. You would think that I would have been on top of this issue but I was taken completely by surprise to learn that the US Senate yesterday unanimously passed a resolution making DST permanent

That does not mean that the deed is done. The House of Representatives has not passed the measure and Joe Biden has not stated that he will sign the bill into law.
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What is so hard about the ‘hard problem’ of consciousness?

I am a materialist in the sense that I think that all phenomena arise due to material entities interacting according to laws of nature. I have seen no reason to think that anything supernatural or mystical is needed to be invoked to explain anything. I have sometimes been asked by people, usually the religious seeking to challenge my atheistic viewpoint that the material world is all there is and does not allow for any gods, as to how I can explain love. They seem to think that love is an immaterial quantity and that believing in its existence requires the same leap of faith as believing in a god. I reply that love is an emotion that is created by the workings of my brain that releases certain substances that cause me to have that feeling I point out that when I die, any love that I feel for anyone or anything will die with me. It does not survive the death of my brain.
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