When people have a terminal illness and are confronted with the real possibility of imminent death, one cannot fault them for taking desperate measures in the hope of a miracle cure. This was what we saw in the early days of the AIDS epidemic when people were dying in large numbers and there was no effective treatment. Sufferers felt that the conventional protocols for finding treatments that depended on the usual three phases of trials to ensure safety and efficacy were far too slow and that seriously ill patients should be allowed to try experimental treatments that had not met the standards for approval.
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