Greta Christina is appealing to the secular community to come to the aid of three young children who have become orphaned as a result of their mother being the victim of a murder-suicide. The mother was a nonbeliever just getting publicly involved in organized atheism, still very much a difficult thing to do in the US especially in the African-American community.

The tragedy seems to have had nothing to do with atheism (as far as I know). But as Greta says,

A member of our community has been murdered. She was a victim of domestic violence. And we have a lousy safety net in this country, which is going to make things even harder on her kids in this already terrible situation.

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